Ukulungiswa kweprocaine kunye neprocaine hcl

Isiseko seprocaine

CAS: 59-46-1

Ukubonakala: umgubo omhlophe wekristale

Indawo yokunyibilika (indawo ebilayo): 59 ~ 62 ℃

Ifomula yemolekyuli: c13h2on2o2

Ubunzima bemolekyuli: 236.31

Procaine hcl

CAS: 51-05-8

Kwi-250ml i-flask ezintathu zentamo ene-stirrer kunye ne-thermometer, isisombululo se-nitrocaine kunye ne-pH ye-4.0-4.2 yongezwa.Ngaphantsi kokuvuselela ngokupheleleyo, umgubo wentsimbi osebenzayo wongezwa kwi-25 ℃ ngamaxesha amaninzi.Emva kokongeza, ubushushu bokusabela buphakama ngokuzenzekelayo kwaye bugcine i-40-45 ℃.Ixesha lokuphendula laliyi-2 iiyure.Emva kokucoca, i-residu yokucoca ihlanjwe kabini ngamanzi amancinci, isisombululo sokuhlamba sidibaniswe ne-filtrate, i-acidified ukuya kwi-pH 5 kunye ne-dilute hydrochloric acid (10%), kunye ne-saturated sodium sulfide solution yongezwa kwi-pH 7.8- 8.0 ukunyusa ityuwa yentsimbi kwisisombululo sokusabela.I-filtrate i-acidified kwi-ph6 kunye nenani elincinci le-dilute hydrochloric acid, kwaye emva koko ishushu kwi-50-60 ℃ imizuzu eyi-10 kunye nenani elincinci lekhabhoni esebenzayo.Intsalela yokucoca ihlanjwe kanye ngenani elincinci lamanzi, isisombululo sokuhlamba sidibaniswe ne-filtrate, sipholile ukuya ngaphantsi kwe-10 ℃, kwaye i-alkalized kunye ne-20% ye-NaOH de i-procaine ihlulwe ngokupheleleyo (pH 9.5-10.5).Hlunga, hlamba kabini, cofa kwaye ukhuphe ukwenza ityuwa (procaine hcl)