Ukusukela ngonyaka ka-2007, singabanye abakhokelayoi-orlistat powderumthengisi eTshayina
I-Orlistat (i-CAS NO.96829-58-2) iyeza elenzelwe ukunyanga ukukhuluphala.Isetyenziselwa ikakhulu ukuthintela ukufunxwa kwamafutha ekudleni komntu, oko kunciphisa i-caloric intake.Ngaphandle koko, yenzelwe ukusetyenziswa ngokubambisana nogqirha-ugadiwe ukunciphisa-calorie ukutya.
| Into | Iimfuno | Iziphumo zovavanyo |
| Imbonakalo | ngelixa uphuma-ngexesha elingumgubo | Umgubo omhlophe |
| Ukuchongwa | Ixesha lokugcinwa kwe-HPLC | Iyahambelana |
| Indawo yokunyibilika | 42 ºC -45°C | 42°C-44°C |
| Ukujikeleza okuthe ngqo | -31.0 ° ~ -41.0 ° | -36.0 ° |
| Ubunyulu yi-HPLC | hayi ngaphantsi kwe 98.0% | 98.5% |
| Ukungcola ngokupheleleyo | hayi ngaphezulu kwe-2.0% | 1.6% |
| Ukungcola komntu ngamnye | hayi ngaphezulu kwe-0.5% | 0.3% |
| Isiqulatho samanzi%(K&F) | hayi ngaphezulu kwe-0.5% | 0.1% |
| Izinyibilikisi ezishiyekileyo | I-EtOH ayikho ngaphezulu kwe-0.5% | ND |
| I-EtAC ayikho ngaphezulu kwe-0.5% | ND | |
| n-Heptane hayi ngaphezulu kwe-0.5% | ngaphantsi kwe-0.1% | |
| Intsalela ekutshisweni | ngaphantsi kwe-0.2% | 0.10% |
| Iintsimbi ezinzima njengePb | hayi ngaphezulu kwe 20ppm | ngaphantsi kwe20ppm |
| Uvavanyo (HPLC) | hayi ngaphantsi kwe 98.0% | 99.60% |
| Ukuqukumbela | Iyahlangabezana neeMfuno | |
I-Orlistat yindlela entsha eyaziwayo kumazwe ngamazwe yeyeza lokunciphisa umzimba.Igama layo lentengiso nguSainike kwaye laqala ukuthengiswa eNew Zealand ngo-1998. I-Orlistat yi-inhibitor ye-gastrointestinal lipase inhibitor yexesha elide kwaye isebenza kakhulu, kwaye ayinyibiliki emanzini, i-soluble kwi-chloroform, kwaye i-soluble lula kwi-ethanol.
I-Orlistat ingasetyenziselwa ukunyanga ukukhuluphala.Ngokuqhelekileyo, umthamo we-120mg uthathwa kathathu ngosuku kwiyure enye yokutya.Ukwehla kobunzima buqala ukwenzeka emva kweeveki ezimbini zokusetyenziswa.Ingasetyenziswa ngokuqhubekayo kwiinyanga ze-6-12, kwaye iziphumo zayo ziya kuyeka ukwanda emva kokuba umthamo wemihla ngemihla udlula i-400mg.Eli chiza lifanelekile ukuba lisetyenziswe ngokudityaniswa nokutya okunekhalori ephantsi ngabantu abatyebe ngokugqithiseleyo nabatyebe kakhulu, kwaye linokusetyenziswa njengonyango lwexesha elide kwizigulana eziye zajongana nezinto ezinobungozi ezinxulumene nobunzima.I-Orlistat inomphumela wokulawula ubunzima bexesha elide elinciphisa kwaye ligcine ubunzima kunye nokuthintela ukuphindaphinda.Ukusebenzisa i-Orlistat kunokunciphisa iziganeko zemingcipheko enxulumene nobunzima kunye nezifo, kuquka i-hypercholesterolemia, uhlobo lwe-2 yesifo sikashukela, ukunyamezela kwe-glucose ukunyamezela, i-hyperinsulinemia, kunye ne-hypertension, kwaye inokunciphisa umxholo weoli kwizitho.I-Orlistat iphinda ilungise amanqanaba e-lipid egazi: inokunciphisa i-serum triglycerides (TG) kunye ne-low density lipoprotein cholesterol (LDL-C), kwaye inokunyusa umlinganiselo we-lipoproteins ephezulu yokuxinana kwi-lipoprotein ephantsi kwizigulane ezityebileyo.
IHebei Guanlang Biotechnology Co., Ltd. yeyaseGuanlang Group, eyasekwa ngonyaka ka-2007, ikwidolophu yaseShijiazhuang eyinkunzi yePhondo leHebei kunye necandelo le-hub phakathi kweBeijing Tianjin kunye neHebei kwaye inenzuzo yokuhamba ngokulula.Inkampani yethu lishishini lemichiza lanamhlanje elinobuchwephesha obuphezulu kunye noPhando kunye noPhuhliso, imveliso kunye nokuthengisa. Sinefektri yethu kunye nelebhu, sikwabonelela ngenkonzo yokudibanisa eyenzelwe abathengi bethu.
